Best Vertical Mice of 2026

The Logitech MX Vertical is a premium ergonomic mouse designed to reduce muscle strain and wrist pressure. Featuring a unique 57-degree tilt, high-precision 4000 DPI sensor, and seamless multi-device connectivity via Logitech Flow, it bridges the gap between medical-grade ergonomics and high-end productivity. While it lacks some of the hyper-fast scrolling features of the MX Master series, its build quality and long-term health benefits make it a staple for office environments.

The Logitech Lift is a vertical ergonomic mouse specifically engineered for users with small to medium-sized hands. By positioning the hand in a natural "handshake" posture at a 57-degree angle, it significantly reduces pressure on the wrist and forearm. It features silent click buttons, a SmartWheel for precision and speed, and dual connectivity via Bluetooth or Logi Bolt. While it lacks some of the premium metal finishes of the larger MX Vertical, its accessible design and software customization via Logi Options+ make it a top contender for office and home use.

The J-Tech Digital V628 is a pioneering vertical mouse designed to combat repetitive strain injuries (RSI) and carpal tunnel syndrome. By shifting the hand into a 57-degree "handshake" position, it reduces forearm twisting. While it lacks the high-end sensors of gaming mice, its utility for office professionals and heavy computer users remains unparalleled in the budget category.

The Perixx Perimice series, particularly the 513 and 713 models, has established itself as the leading alternative to high-end ergonomic mice. By prioritizing a 60-degree vertical angle, these mice reduce muscle strain and prevent repetitive strain injuries (RSI). While the build quality reflects its budget-friendly nature, the functional benefits for office workers and students are undeniable.